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A renaissance for the tumor immunosurveillance hypothesis

Article Abstract:

Research presented concerns the theory that the immune system can provide surveillance against cancer, focusing on the molecular mechanisms involved in immunosurveillance for spontaneous tumors, or tumors induced by carcinogens. Research suggests that T cells that express the alphabeta-T-cell receptor have a role in the prevention of cutaneous cancer caused by carcinogens.

Author: Lanier, Lewis L.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
United States, Cellular control mechanisms, Cell regulation, Tumors

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No tolerance for depletion

Article Abstract:

T-cell depletion is commonly used in strategies that attempt to influence the immune system into tolerating foreign tissue after transplantation. Studies in mice now suggest that restoration of regulatory T-cells allows susceptibility to tolerance to reemerge.

Author: Auchincloss, Hugh
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2004
Health Care and Social Assistance, HEALTH SERVICES, Surgical Transplants, Transplantation of organs, tissues, etc., Transplantation

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Dendritic cells: versatile controllers of the immune system

Article Abstract:

A research work related to the dendritic cells and its influence on immune system and other disease-related stimuli is reviewed.

Author: Steinman, Ralph M.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2007
Health aspects, Dendrites

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Subjects list: Research, T cells, Immune system
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