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A reversible posterior leukoencephalopathy syndrome

Article Abstract:

Acutely ill patients may have an episode of reversible leukoencephalopathy, a disease of the white matter in the brain. Brain scans showed extensive brain abnormalities in 15 patients with kidney disorders and/or sudden onset of high blood pressure. Seven patients were receiving immunosuppressive drugs after transplantation or to treat aplastic anemia. The abnormal scans were thought to reveal swelling in the back regions of the brain. Patients had seizures, headaches, vomiting, confusion, blindness, and other vision impairments. Mental alertness typically decreased. Within two weeks, treatment with antihypertensive drugs resolved leukoencephalopathy among all patients. Although various factors can cause reversible leukoencephalopathy, hypertension, immunosuppressive therapy, kidney failure, and fluid retention all contribute to this syndrome.

Author: Caplan, Louis R., Mas, Jean-Louis, Lamy, Catherine, Pessin, Michael S., Hinchey, Judy, Chaves, Claudia, Appignani, Barbara, Breen, Joan, Pao, Linda, Wang, Annabel
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1996
Diagnosis, Cerebral edema, Antihypertensive drugs, Antihypertensive agents, Leukoencephalopathy

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Patent foramen ovale in young adults with unexplained stroke

Article Abstract:

A discussion on patent foramen ovale occurring in young patients or middle-aged patients who have minimal risk factors for atherosclerosis and in whom evaluations for vascular disease or systemic illnesses are negative is presented. In patients with cryptogenic stroke, assessment for patent foramen ovale and other potential cardiac sources of embolism is recommended.

Author: Devereux, Richard B., Kizer, Jorge R.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
United States, Science & research, Research, Prevention, Young adults, Heart septum

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Recurrent cerebrovascular events associated with patent foramen ovale, atrial septal aneurysm, or both

Article Abstract:

Stroke patients who have certain heart defects have a greater risk of a second stroke than stroke patients without these defects. This was the conclusion of a study of 581 stroke patients, some of whom had an atrial septal defect.

Author: Mas, Jean-Louis, Arquizan, Caroline, Lamy, Catherine, Zuber, Mathieu, Cabanes, Laure, Derumeaux, Genevieve, Coste, Joel
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2001
Complications, Atrial septal defects

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Subjects list: Health aspects, Risk factors, Stroke (Disease), Stroke
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