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A trial of contraceptive methods in women with systemic lupus erythematosus

Article Abstract:

A single blind clinical trial is conducted involving 162 women with systemic lupus erythematosus who were randomly assigned to combined oral contraceptives, a progestin-only pill or a copper intrauterine device (IUD). Results show that although estrogen-containing oral-contraceptive regimen do not appear to increase the risk of disease exacerbation in women with systemic lupus erythematosus, one should still be cautious about the possibility of an increased risk of thrombosis with hormonal methods of contraception.

Author: Sanchez-Guerrero, Uribe, America G., Lara-Reyes, Pilar, Seuc, Armando H., Jimenez-Santana, Luisa, Mestanza-Peralta, Marilu, Cravioto, Maria-del-Carmen
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
Health aspects, Methods, Clinical trials, Women's health, Systemic lupus erythematosus, Contraception

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Thinking outside the box

Article Abstract:

The case of a 35-year-old man with advanced acquired immunodeficiency syndrome (AIDS) is used to highlight the challenges clinicians face in the diagnosis of acute pulmonary embolism. The case illustrates the importance of 'thinking outside the box' in order to avoid missing this diagnosis, particularly in patients whose underlying diseases might otherwise suggest alternative explanations for presenting symptoms.

Author: Farzaneh-Far, Ramin, Schwarzberg, Talya, Mushlin, Stuart B.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2006
New England States, Case studies, Diagnosis, Pulmonary embolism

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Subjects list: New England
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