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AAVant-garde gene therapy

Article Abstract:

The authors discuss how the use of adeno-associated virus (AAV) to deliver canine factor IX gene in dogs was able to partially correct hemophilia B. Although they do not see this process readily converted to use in humans, they think it will be useful for research in gene therapy.

Author: Woo, Savio L.C., Linden, R. Michael
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999
Health aspects, Research, Genetic vectors, Virus-vector relationships

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Acromegaly

Article Abstract:

Advances in the understanding and treatment of acromegaly are discussed. It is believed that understanding the development, function, and regulation of somatotroph cells provides insights into the cellular origin of this tumor as well as approaches to the treatment of acromegaly.

Author: Melmed, Shlomo
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2006
United States, Care and treatment, Causes of, Risk factors, Acromegaly, Disease/Disorder overview

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