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Accuracy of fecal occult blood screening for colorectal neoplasia: a prospective study using Hemoccult and HemoQuant tests

Article Abstract:

Fecal occult blood testing may not be an effective method to screen for colorectal cancer. Occult blood is a small amount of blood in the feces that cannot be seen but can be detected using chemical tests. Among 13,529 individuals who underwent fecal occult blood testing using the Hemoccult and HemoQuant tests, 1,217 were patients over 18 years old who had undergone surgery for colorectal cancer and 12,312 were relatives over 50 years old of patients with colorectal cancer. Forty-seven colorectal cancer recurrences or new colorectal cancers occurred among the patients who had undergone surgery. Only 26% of these cancers were detected using either the Hemoccult or HemoQuant tests. Forty-two colorectal cancers occurred among the relatives of colorectal cancer patients. Four percent of these cancers were detected using the Hemoccult test and six percent were detected using the HemoQuant tests.

Author: Moertel, Charles G., Ahlquist, David A., Loprinzi, Charles L., Wieand, Harry S., Gerstner, James B., O'Connell, Michael J., McGill, Douglas B., Ellefson, Ralph D., Malliard, James A., Pandya, Kishan
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1993
Measurement, Occult blood

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Follow-up testing for curatively treated cancer survivors: what to do?

Article Abstract:

Cancer survivors should be followed up after curative treatment using guidelines that will provide improved care. Data should be collected from: large clinical studies that address testing procedures that detect recurrent disease; procedures that provide good rates of survival; sites where cancer can be cured; and prognosis based on timing of first cancer diagnosis. Tests, x-rays, and surgery should be performed when it is necessary and would contribute to the patient's well-being. Intensive testing and treatment may not contribute to the patient's quality of life, and may not positively affect survival. The cost constraints imposed on health care prompts physicians to make wise use of resources.

Author: Loprinzi, Charles L.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1995
Care and treatment, Editorial, Cancer patients

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Predicting Advanced Proximal Colonic Neoplasia With Screening Sigmoidoscopy

Article Abstract:

Patients whose first colonoscopy shows they have a type of intestinal polyp called tubulovillous or villous adenoma should receive follow-up colonoscopies on a regular basis. Colonoscopy is a technique for examing the colon. In a group of 2,972 people 50 or older who had an initial sigmoidoscopy, 12% of those who had tubulovillous or villous adenoma were found to have cancer on a repeat colonoscopy six months later. This was true in only 5% of those with polyps classified as tubular adenomas.

Author: Selby, Joe V., Ackerson, Lynn, Levin, Theodore R., Palitz, Albert, Grossman, Seymour, Conell, Carol, Finkler, Laura, Rumore, Greg
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1999
Colonoscopy

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Subjects list: Diagnosis, Colorectal cancer, Intestinal polyps
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