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Dysregulation of beta-chemokines in the lungs of HIV-1-infected patients

Article Abstract:

Abnormal levels of beta-chemokines in the lung may explain why many HIV patients develop lung diseases, according to a study of 19 HIV-infected patients and 5 HIV-negative people. Beta-chemokines are chemicals produced by the immune system.

Author: Toossi, Zahra, Aung, Htin, McKenna, Siobhan M., Ketoff, Nabila R., Jones, Leola, Wu, Mianda, Hejal, Rana, Rich, Elizabeth A.
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2001
Lung diseases, Cytokines

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Increased replication of HIV-1 at sites of Mycobacterium tuberculosis infection: potential mechanisms of viral activation

Article Abstract:

Research has been conducted on HIV-1 replication echancement by tuberculosis. Results demonstrate that at Mycobacterium tuberculosis infection sites conditions are propitious for HIV-1 transcriptional activation in latently infected mononuclear cells and for viral infection facilitation of newly recruited cells.

Author: Toossi, Zahra, Aung, Htin, Wu, Mianda, Mugyenyi, Peter, Johnson, John L., Kanost, Richard A., Luzze, Herry, Peters, Pierre, Okwera, Alphonse, Joloba, Moses, Mugerwa, Roy D., Ellner, Jerrold J., Hirsch, Christina S.
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2001
Science & research, Uganda, Labor Distribution by Employer, Care and treatment, Research, Methods, Case studies, Prevention, Statistics, HIV patients, Cells (Biology), Tuberculosis, Cells, Epidemiology, AIDS treatment

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Activation of latent HIV-1 by Mycobacterium tuberculosis and its purified protein derivative in alveolar macrophages from HIV-infected individuals in vitro

Article Abstract:

Mycobacterium tuberculosis and its purified protein derivative (PPD) can activate HIV in macrophages from HIV-positive patients. The virus was not activated in macrophages from patients without detectable virus in their blood.

Author: Toossi, Zahra, Rich, Elizabeth A., Nicolacakis, Katherina, Xia, Liang, Ferrari, Nicole A.
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1997
Statistical Data Included, Macrophages

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Subjects list: Health aspects, Causes of, Physiological aspects, HIV infection, HIV infections, United States, Mycobacterium tuberculosis
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