Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2

Article Abstract:

Research demonstrates the synergistic induction of vascular networks by a combination of two angiogenic factors, platelet-derived growth factor-BB and fibroblast growth factor-2 therapy. Furthermore, the angiogenic factors stimulate collateral arteriogenesis in the ischemic hind limbs following ligation of the femoral artery in both rat and rabbit.

France, Sweden, Drug therapy, Ischemia, Arteries, Vascular smooth muscle, Company growth

---

Long-term cure of the photosensitivity of murine erhthropoietic protoporphyria by preselective gene therapy

Article Abstract:

The photosensitivity of erythropoietic protoporphyria in mice might be treated using preselective gene therapy. So far no real cure of an animal model of a human disease has been achieved using gene transfer into hematopoietic stem cells in the absence of spontaneous in vivo selection for transduced cells.

Statistical Data Included, Research, Genetic aspects, Cellular signal transduction, Hematopoietic stem cells, Physiology, Photosensitivity disorders

---

Cartilage to bone - angiogenesis leads the way

Article Abstract:

Vascular endothelial growth factor (VEGF) has a vital role in longitudinal bone growth by stimulating angiogenesis into the epiphyseal growth plate. Soluble VEGF receptors target only newly forming blood vessels apparently not affecting blood vessels already in existence.

Bones, Vascular endothelial growth factor, Cartilage, Bone development

Similar abstracts:

• Abstracts: Changing the medical school curriculum to improve patient access to primary care. Improving the supply of physicians in rural areas
• Abstracts: Increased cost and rates of use in the California workers' compensation system as a result of self-referral by physicians
• Abstracts: Trends in prevalence, awareness, treatment, and control of hypertension in the United States, 1988-2000. Hypertension prevalence and blood pressure levels in 6 European countries, Canada, and the United States
• Abstracts: Researchers dissect the tick and tock of the human body's master clock. Insomniac artists explore night's terrain
• Abstracts: Making "connexions": enhancing the therapeutic potential of patient-clinician relationships. What do doctors find meaningful about their work?

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.