Anticoagulation therapy for stroke prevention in atrial fibrillation: how well do randomized trials translate into clinical practice?

Article Abstract:

The anticoagulant drug warfarin is effective in reducing the risk of stroke in people who have atrial fibrillation, according to a study of 11,526 members of Kaiser Permanente of Northern California. This study shows that warfarin can be used in primary care situations, although 80% of the people involved in this study went to an anticoagulant clinic to receive warfarin. Atrial fibrillation occurs when the upper part of the heart begins beating too fast.

Evaluation

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Effect of intensity of oral anticoagulation on stroke severity and mortality in atrial fibrillation

Article Abstract:

Patients with a heart condition called atrial fibrillation should take a dosage of warfarin that will achieve an international normalized ratio (INR) of 2 or greater. Lower doses will increase their risk of stroke and the stroke will be more severe than at higher doses. They will also be more likely to die from the stroke if they take a lower dose of warfarin.

Patient outcomes, Complications and side effects, Prognosis, Dosage and administration

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Prevalence of Diagnosed Atrial Fibrillation in Adults: National Implications for Rhythm Management and Stroke Prevention

Article Abstract:

About 2.3 million American adults have atrial fibrillation, and the condition is more common in men, whites, and the elderly. By 2050, 5.6 million could be affected as the population ages. Atrial fibrillation occurs when the upper part of the heart begins to beat very rapidly, which can cause a stroke.

Statistical Data Included, Statistics

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