Assessment of Laboratory Tests for Plasma Homocysteine--Selected Laboratories, July-September 1998

Article Abstract:

Fluorescence polarization immunoassay (FPIA) appears to be more reliable than other methods for measuring blood levels of homocysteine. Elevated blood levels of this amino acid have been linked to a higher risk of cardiovascular disease. The Centers for Disease Control evaluated homocysteine measurements performed at 14 different laboratories. Some used high-performance liquid chromatography (HPLC), others gas chromatography-mass spectrometry (GC-MS), and others used FPIA. FPIA produced the least variation when used by different labs on the same blood samples.

Measurement, Medical laboratories, Biomedical laboratories, Homocysteine

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Assessment of Commercial Laboratories Performing Hair Mineral Analysis

Article Abstract:

Commercial laboratories in the US that do hair analysis are unreliable. Researchers sent pieces of one hair from one volunteer to six different laboratories. All six gave different results for most minerals and even used different reference values to determine what a normal mineral level should be. They also provided different dietary advice based on the results.

Biological laboratories

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The Uncertainty of Hair Analysis for Trace Metals

Article Abstract:

It may be inherently difficult to accurately measure trace elements and minerals in hair samples. A study published in 2000 found that six laboratories that analyze hair samples produced different results. Hair may contain many contaminants that are difficult to remove.

Editorial, Testing laboratories

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