Bad medicine

Article Abstract:

Secomet V, an herbal product manufactured by the South African firm, Secomet, from the red clover, Trifollium pratense, is claimed to be effective in AIDS treatment, but this product has never been clinically tested, nor do its makers know how it works. Some clinicians are concerned that this product could damage the liver as patients using this medicine are found to have abnormal liver enzymes. The University of Cape Town is expected to make a public statement on this product.

South Africa, Pharmaceutical industry, Complications and side effects, Secomet V (Medication)

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Prospects for plant-derived antibacterials

Article Abstract:

The aspect of plant defense response to recognize specific pathogens and develop an enormous variety of small-molecule antimicrobials are discussed which could be used to develop useful antibiotics. It is concluded that in order to become a viable lead compound, a plant-derived substance must show specificity against a particular target that is absent in humans which increases the likelihood of developing a nontoxic antibacterial.

United States

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Riboswitches as antibacterial drug targets

Article Abstract:

Riboswitches possess unique qualities among RNAs that serve as drug targets in that they have evolved to form structured and highly selective receptors for small drug-like metabolites and in most cases, metabolite binding to the receptor represses the expression of the gene encoded by the RNA. The experiments validating riboswitches as drug targets, describe the existing technology for riboswitch drug discovery are summarized.

Science & research, Research, Ribosomal RNA, Metabolites

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