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Brimonidine - an alpha(sub)2-agonist for glaucoma

Article Abstract:

Brimonidine tartrate has been approved for the treatment of open-angle glaucoma and ocular hypertension. It is an alpha(sub)2-adrenergic agonist that works by increasing the outflow of aqueous humor, which lowers intraocular pressure. Clinical trials have established its effectiveness in lowering intraocular pressure without adversely affecting the heart. Adverse effects include eye redness or stinging and dry mouth. Marketed under the trade name Alphagan, it is more expensive than many other drugs used to treat glaucoma.

Publisher: Medical Letter, Inc.
Publication Name: Medical Letter on Drugs and Therapeutics
Subject: Health
ISSN: 0025-732X
Year: 1997
Product/Service Evaluation, Drug therapy, Alphagan (Medication)

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Alpha-, beta-, gamma-globulin - Arne Tiselius and the advent of electrophoresis

Article Abstract:

The impact of Swedish biologist Arne Tiselius' studies of protein electrophoresis on the medical sciences is evaluated. His electrophoresis techniques are now being used in modern biochemical, clinical and molecular biology laboratories. Tiselius work on gamma-globulins is also widely used in immunology research. After ceasing experimental research, Tiselius remained active in supporting other fields of scientific research.

Author: Putnam, Frank W.
Publisher: Johns Hopkins University Press
Publication Name: Perspectives in Biology and Medicine
Subject: Health
ISSN: 0031-5982
Year: 1993
Research, Analysis, Medical research, Electrophoresis, Immunological research, Immunologic research, Gamma globulins, Tiselius, Arne

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WHAT IS GLAUCOMA?

Article Abstract:

Glaucoma is an eye disease that causes progressive and irreversible damage to the optic nerve, resulting in loss of peripheral visual field and eventual blindness. Diagnosing Glaucoma is often difficult because the damage to the optic nerve ranges from low to high, which may not correlate with loss of peripheral visual field.

Author: RAMANATHAN, SARAS, ERNEST, J. TERRY
Publisher: Johns Hopkins University Press
Publication Name: Perspectives in Biology and Medicine
Subject: Health
ISSN: 0031-5982
Year: 1998
Development and progression, Diseases, Eye diseases, Peripheral vision

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Subjects list: Evaluation, Glaucoma
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