COX-1-Sparing NSAIDs--Is the Enthusiasm Justified?

Article Abstract:

More research is needed to determine if COX-2 inhibitors are cost-effective for treating arthritis pain. COX-2 inhibitors are drugs that inhibit an enzyme called cyclooxygenase-2 (COX-2). Two COX-2 inhibitors have been approved by the FDA: celecoxib and rofecoxib. Two 1999 studies found that both drugs appear to have fewer gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs (NSAIDs). However, the risk of these side effects is very small in most people and COX-2 inhibitors are expensive. They may only be cost-effective in certain patients, such as elderly people with a history of ulcers.

Health aspects, Editorial, Drug therapy, Arthritis, Rofecoxib

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Imperial airways

Article Abstract:

A number of UK firms have won major contracts on the building of the new Chek Lap Kok airport in Hong Kong. Foster Associates are the second in command on the architectectural team and have a team of 50-60 staff. The terminal building will be 1.4 kilometres long and the artificial island will be the secondest largest man-made structure visible from space. AMEC have won the 280 million pounds sterling North Lantau Expressway; Costian have won the 750 million pounds sterling site preparation contract and Trafalgar House have won the 550 million pounds sterling Tsing Ma suspension bridge contract.

Design and construction, Hong Kong, Airports

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Steel mill minimizes downtime

Article Abstract:

Steel milldowntime relies greatly on a very efficient control system. Gerrard and Co's cold-strip steel facility in Florence, AL, used to employ a rotating analog control system which became inefficient in time. After the old system broke down, Gerrard and systems integrator Electric Machine Control Inc thought of using an input/output system applicable to programmable controllers. The new system lessened the downtime and maintenance costs while increasing production and quality.

Cold finishing of steel shapes, Usage, Equipment and supplies, Steel industry, Control systems, Mills and mill-work, Mills, A.J. Gerrard and Co.

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