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Beta-carotene in HIV infection

Article Abstract:

Beta-carotene may help prevent opportunistic infections in individuals infected with HIV by stimulating the immune system. Carotenes are a group of yellow-red pigments that are precursors to vitamin A, a substance associated with reduced severity and frequency of infections. Twenty-one HIV-infected individuals were treated with 180 milligrams per day of beta-carotene for four weeks and with a placebo, or an inactive substance, for four weeks. The total white blood cell count and CD4 T-cell count increased during treatment with beta-carotene, compared with placebo treatment. CD4/CD8 T-cell ratios also improved during treatment with beta-carotene compared with placebo treatment. Treatment with beta-carotene did not increase absolute numbers of CD4 T-cells significantly.

Author: Nelson, Heidi D., Coodley, Gregg O., Loveless, Mark O., Folk, Cathi
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes
Subject: Health
ISSN: 0894-9255
Year: 1993
Health aspects, HIV infection, Drug therapy, HIV infections, Beta carotene

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Inhibition of HIV-1 replication by an aqueous extract of Spirulina platensis (Arthrospira platensis)

Article Abstract:

A water extract of the blue-green algae Arthrospira platensis, which was formerly called Spirulina platensis, seems able to prevent reproduction of the HIV-1 virus in laboratory situations. The extract was incubated with the virus, then added to human T-cell lines, where it was inactive. Closer analysis showed definite antiviral activity. While these tests were in a laboratory and not in either a human or animal body, they indicate an antiretroviral aspect that may be clinically significant.

Author: Baba, Timothy W., Ayehunie, Seyoum, Ruprecht, Ruth M., Belay, Amha
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Subject: Health
ISSN: 1077-9450
Year: 1998
Testing, HIV (Viruses), HIV, Antiviral agents, Virus replication, Spirulina

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