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Chemoprevention of colorectal cancer

Article Abstract:

Certain drugs and nutrients may lower the risk of colorectal cancer. Aspirin and other non-steroidal anti-inflammatory drugs may lower the risk of colorectal cancer, but they also have long-term side effects. The consumption of fruits and vegetables has been linked to a lower risk of colorectal cancer. This effect may be due to folic acid, which is abundant in fruits and vegetables. Dietary calcium may also reduce the risk of colorectal cancer. Women have a lower risk of colorectal cancer than men, and this may be due to the increased use of estrogen replacement therapy.

Author: Mayer, Robert J., Janne, Pasi A.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
Folic acid, Hormone therapy

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Calcium supplements for the prevention of colorectal adenomas

Article Abstract:

Calcium supplementation may prevent colorectal cancer, although the effect appears to be small. Researchers randomly assigned 832 people with a history of colorectal cancer to take 1200 milligrams of calcium or a placebo every day for up to four years. Colonoscopies were performed one and four years after the study began. Thirty-one percent of those taking calcium had a recurrence of their cancer, compared to 38% of those on placebo. This represents a 19% lower risk of cancer recurrence in those taking calcium. Those taking calcium who had a recurrence had fewer tumors.

Author: Baron, J.A., Beach, M., Mandel, J.S., Van Stolk, R.U., Haile, R.W., Sandler, R.S., Rothstein, R., Summers, R.W., Snover, D.C., Beck, G.J., Bond, J.H., Greenberg, E.R.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1999
Cancer recurrence

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Systematic therapy for colorectal cancer

Article Abstract:

Colorectal cancer is considered as the third most common malignant disease and the second most cause of cancer-related death in the United States. Newer cytotoxin chemotherapies and biologic agents effective against colorectal cancer are considered and their uses fro the treatment of metastatic disease and as components of adjuvant therapy are examined.

Author: Mayer, Robert J., Meyerhardt, Jeffrey A.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
United States, Drug therapy, Dosage and administration, Chemotherapy

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Subjects list: Health aspects, Prevention, Colorectal cancer, Calcium (Nutrient), Calcium, Dietary, Cancer
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