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Chemotherapy with preoperative radiotherapy in rectal cancer

Article Abstract:

The effect of addition of chemotherapy to preoperative radiotherapy and the use of postoperative chemotherapy in the treatment of T3 or T4 resectable rectal cancer is examined. It is concluded that adding fluorouracil-based chemotherapy preoperatively or postoperatively to rectal cancer patients treated with preoperative radiotherapy has no significant effect on survival, but chemotherapy provides a significant benefit to local control regardless of timing.

Author: Collette, Laurence, Bosset, Jean-Francois, Maingon, Philippe, Calais, Gilles, Mineur, Laurent, Radosevic-Jelic, Ljiljana, Daban, Alain, Bardet, Etienne, Beny, Alexander, Ollier, Jean-Claude
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2006
New England States

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Preoperative versus postoperative chemoradiotheraphy for rectal cancer

Article Abstract:

The preoperative chemoradiotherapy is compared with preoperative chemoradiotherapy for locally advanced rectal cancer. As compared to preoperative chemoradiotherapy, preoperative chemoradiotherapy has improved local control and is associated with reduced toxicity.

Author: Sauer, Rolf, Rodel, Claus, Martus, Peter, Hess, Clemens F., LIersch, Torsten, Hohenberger, Werner, Becker, Heinz, Fietkau, Rainer, Wittekind, Christian, Hafer, Eva, Raab, Rudolf, Schmidberg, Heinz, Tschmelitsch, Jorg, Karstens, Johann-H
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
United States, Analysis, Toxicity

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Prophylactic cranial irradiation in extensive small-cell lung cancer

Article Abstract:

The benefit of chemotherapy administered to patients with small-cell lung cancer and the survival rate is presented.

Author: Collette, Laurence, Slotman, Ben, Faivre-Finn, Corinne, Krammer, Gijs, Rankin, Elaine, Snee, Michael, Hatton, Matthew, Postmus, Pieter, Musat, Elena, Senan, Suresh
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
Health aspects, Drug therapy, Cancer survivors, Lung cancer, Small cell, Small cell lung cancer, Clinical report

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Subjects list: Care and treatment, Usage, Colorectal cancer, Cancer, Radiotherapy, Chemotherapy
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