Chlamydia trachomatis, infertility, and population growth in sub-Saharan Africa

Article Abstract:

The greater effort to control the spread of sexually transmitted diseases (STDs) in Africa may lead to a surge in population growth. The most common causes of infertility among women in sub-Saharan Africa are gonorrhea and chlamydia. As more treatment programs are introduced as part of expanded AIDS prevention programs, there may be a decrease in the spread of STDs and the infertility that often accompanies them. A mathematical model originally devised to predict the effect of the spread of gonorrhea on population growth has been applied to the spread of chlamydia. According to the model, gonorrhea causes a greater decline in population growth than chlamydia because of gonorrhea's higher transmission and infection rates. Contraceptive counseling will need to be a part of any STD education program if a population surge is to be avoided.

Health aspects, Models, Demographic aspects, Chlamydia trachomatis, Infertility, Female, Female infertility, Sub-Saharan Africa, Population forecasting

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Impact of improved laboratory compliance on notification of genital Chlamydia trachomatis infection in Victoria

Article Abstract:

Several changes in the administrative process may improve the Australian Health Department's ability to track Chlamydia infections. The notification patterns of laboratories and primary doctors were analyzed during a two-month period in Victoria, Australia. Few laboratories or doctors notified the Health Department within the required seven days following infection identification. However, nearly all of the doctors but only 48% of the laboratories had notified the department within three weeks of identification. Reminder calls to the laboratories resulted in the most significant response rate improvement. Many doctors were unclear about the reporting procedures.

Sexually transmitted diseases, Reports, Diagnosis, Medical laboratories, Biomedical laboratories, Disease reporting

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Interferon-gamma and interleukin-5 production by mice in response to genital infection by the mouse pneumonitis agent of Chlamydia trachomatis

Article Abstract:

Interleukin-5 may be associated with increased genital inflammation that does not confer immunity, while interferon-gamma may evoke a protective immune response after exposure to Chlamydia trachomatis. Researchers analyzed the effect of C. trachomatis exposure on three groups of mice. Mice with induced inflammation showed increased genital inflammation after C. trachomatis infection but no increase in their immune response. Elevated interleukin-5 levels, and thus inflammation, persisted even after the first Chlamydia infection was over. Chlamydia-related inflammation has been linked to infertility in women.

Physiological aspects, Interferon gamma, Interleukins

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