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Effect of fluoxetine on contractile activity of pregnant rat uterine rings

Article Abstract:

Fluoxetine does not inhibit uterine contractions, according to a study of rat uterine tissue samples exposed to fluoxetine, imipramine, and nortriptyline. Fluoxetine has been linked to premature delivery in pregnant women who take it, but this must occur through some other mechanism.

Author: Saade, George R., Vedernikov, Yuri, Bolanos, Sandra, Bytautiene, Egle, Fulep, Eva, Garfield, Robert E.
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2000
Complications and side effects, Risk factors, Premature labor, Fluoxetine, Serotonin uptake inhibitors, Selective serotonin reuptake inhibitors, Prozac (Medication)

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Contractility of late pregnant rat myometrium is refractory to activation of soluble but not particulate guanylate cyclase

Article Abstract:

Contractions of the uterus are mediated by guanylate cyclase, according to a study of uterine tissue from pregnant rats. Guanylate cyclase in turn is affected by natriuretic peptides, which are naturally occurring hormones produced by the brain and heart.

Author: Saade, George R., Vedernikov, Yuri, Fulep, Eva, Garfield, Robert E.
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2001
Natriuretic peptides, Guanylate cyclase

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Effect of histamine on phasic and tonic contractions of isolated uterine tissue from pregnant women

Article Abstract:

Research has been conducted on histamine. The role of histamine in uterine tissue's plastic and tonic contractive activity has been investigated, and the results have demonstrated that histamine inhibits tonic and increases spontaneous uterine tissue contractions.

Author: Saade, George R., Romero, Roberto, Bytautiene, Egle, Garfield, Robert E., Vedernikov, Yuri P.
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2003
United States, Research and Development in the Physical, Engineering, and Life Sciences, Science & research, Research and Testing Services, Gynecological R&D, Health aspects, Research, Analysis, Pregnant women, Histamine receptors, Myometrium, Obstetrics, Gynecological research

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Subjects list: Uterus, Uterine contractions, Physiological aspects
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