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Coronary stenting plus platelet glycoprotein IIb/IIIa blockade compared with tissue plasminogenn activator in acute myocardial infarction

Article Abstract:

A coronary stent plus the drug abciximab appears to be more effective for heart attack patients than tissue plasminogen activator (tPA), according to a study of 140 patients. A stent is a small cylinder that keeps an artery open, abciximab is an anticoagulant, and tPA breaks up the blood clots that cause most heart attacks.

Author: Schomig, Albert, Kastrati, Adnan, Dirschinger, Josef, Mehilli, Julinda, Schricke, Ullrich, Pache, Jurgen, Martinoff, Stefan, Neumann, Franz-Josef, Schwaiger, Markus
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
Care and treatment

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Platelet glycoprotein IIb/IIIa inhibition with coronary stenting for acute myocardial infarction

Article Abstract:

The anticoagulant drug abciximab appears to improve blood flow and decrease postoperative mortality rates in heart attack patients who receive a stent. Stents are small cylindrical devices that are inserted in arteries to keep them open.

Author: Montalescot, Gilles, Barragan, Paul, Wittenberg, Olivier, Ecollan, Patrick, Elhadad, Simon, Villain, Philippe, Boulenc, Jean-Marc, Morice, Marie-Claude, Maillard, Luc, Pansieri, Michel, Choussat, Remi, Pinton, Philippe
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2001

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Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation

Article Abstract:

A study is conducted enrolling 3491 patients in the age group of 18 to 75 years of age, who presented within 12 hours after the onset of an ST-elevation myocardial infarction and randomly assigned them to receive clopidogrel or placebo. In patients 75 years or younger who have myocardial infraction with ST-segment elevation, the addition of clopidogrel improves the patency rate of the infarct-related artery and reduces ischemic complications.

Author: Gibson, C. Michael, McCabe, Carolyn H., Braunwald, Eugene, Montalescot, Gilles, Sabatine, Marc S., Theroux, Pierre, Skene, Allan M., Hill, Karen A., Claeys, Marc J., Cools, Frank, Lopez-Sendon, Jose L.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2005
United Kingdom, Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Blood Clot Dissolvers, Usage, Plavix (Medication)

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Subjects list: Evaluation, Heart attack, Anticoagulants (Medicine), Anticoagulants, Fibrinolytic agents, Stent (Surgery), Thrombolytic drugs, Stents, Drug therapy
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