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Corticosteroid Therapy in Acute Respiratory Distress Syndrome

Article Abstract:

More research is needed to determine whether corticosteroids are beneficial in acute respiratory distress syndrome (ARDS). ARDS is a serious form of lung failure with mortality rates ranging from 35% to 65% of affected patients. A 1998 study found that high-dose and prolonged methylprednisolone therapy substantially reduced mortality rates in ARDS patients. However, the study was small and may have had design flaws.

Author: Brun-Buisson, Christian MD, Brochard, Laurent MD
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1998
Drug therapy, Corticosteroids, Adrenocortical hormones, Methylprednisolone

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Acute respiratory distress syndrome in critically ill patients with severe acute respiratory syndrome

Article Abstract:

Some people who have severe acute respiratory syndrome (SARS) may develop acute respiratory distress syndrome (ARDS), according to a study of 199 SARS patients in Singapore who had to be hospitalized. Forty-five developed ARDS and had to be admitted to the intensive care unit. Thirty-seven percent of these patients died within 28 days and over half died within 13 weeks.

Author: Lew, Thomas W.K., Kwek, Tong-Kiat, Tai, Dessmon, Earnest, Arul, Loo, Shi, Singh, Kulgit, Kwan, Kim Meng, Chan, Yeow, Yim, Chik Foo, Bek, Siam Lee, Kor, Ai Ching, Yap, Wee See, Chelliah, Y. Rubuen, Lai, Yeow Choy, Goh, Soon-Keng
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2003
Patient outcomes, Causes of, Prognosis, Severe acute respiratory syndrome

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Acute renal failure in critically ill patients: A multinational, multicenter study

Article Abstract:

The first large international investigation of the epidemiology and outcome of acute renal failure (ARF) in critically ill patients is presented. The period prevalence of ARF in intensive care unit patients in multiple countries is determined and the impact of the differences in etiology, illness severity, and clinical practice is characterized.

Author: Schetz, Miet, Uchino, Shigehiko, Bellomo, Rinaldo, Morimatsu, Hiroshi, Bouman, Catherine, Kellum, John A., Gibney, Noel, Doig, Gordon S., Morgera, Stanislao, Tan, Ian, Tolwani, Ashita, Macedo, Ettiene, Ronco, Claudio
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
United States, Science & research, Research, Critically ill, Acute renal failure, Acute kidney failure

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Subjects list: Health aspects, Acute respiratory distress syndrome, Adult respiratory distress syndrome
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