DTP immunization and susceptibility to infectious diseases: Is there a relationship?

Article Abstract:

A recent study has indicated that children are at a higher risk for developing invasive bacterial infection soon after they have been vaccinated with pertussis (whooping cough) vaccine. Another study found that children developed symptoms of infection soon after receiving the diphtheria, tetanus, and pertussis (DTP) vaccine. This study examined if the incidence (number of new cases) of invasive bacterial infection was higher in Native Alaskan infants and children soon after they received the DTP vaccine. This population was chosen because they have a high rate of invasive bacterial disease and the state of Alaska has made a concerted effort to have children vaccinated with DTP and keeps detailed records. Cases of invasive bacterial disease in Native Alaskan children between the ages of 2 and 24 months who had received DTP vaccine were examined. A total of 186 cases and 186 matched controls were evaluated. Results showed that characteristics of the cases and the controls were similar. The number of case subjects who were immunized within 30 days of developing invasive bacterial disease was equal to the number of control subjects who were immunized within 30 days of the reference date. When an analysis was made of all illnesses suffered from 30 days before to 30 days after immunization with both groups combined, the rate of illness was 53 percent prior to and 43 percent following vaccination. These results indicate that the risk for invasive bacterial infection does not increase after Native Alaskan children receive DTP vaccine. (Consumer Summary produced by Reliance Medical Information, Inc.)

Complications and side effects, Risk factors, Bacterial infections, Vaccines, Alaska

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Pertussis in adults

Article Abstract:

Providing booster vaccines against whooping cough for adolescents and adults may better control the continued pattern of whooping cough seen in children. Childhood vaccines or infections do not seem to confer continued immunity for adults. Whooping cough in adults seems to be more widespread than previously thought and can be more easily identified with current laboratory technology. Even though adult cases of whooping cough are usually not severe and frequently go undiagnosed, they provide a convenient vehicle for infecting surrounding children.

Care and treatment, Editorial, Whooping-cough, Whooping cough, Pertussis vaccines

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Poliomyelitis: immunization/prophylaxis for children and adolescents

Article Abstract:

The global rates for poliomyelitis are low, but children and adolescents need to be vaccinated against the disease. The Western Hemisphere was certified as free of the wild-type of virus in 1994, but there is some risk of vaccine-associated poliomyelitis from oral polio vaccine. Many public health authorities recommend a series of vaccinations for children from two months to 6 years.

Poliomyelitis, Poliomyelitis vaccine, Poliovirus vaccines

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