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Determination of interstitial collagenase (MMP-1) in patients with rheumatoid arthritis

Article Abstract:

The level of a protein substance in joint fluid known as MMP-1 may not be useful as an indicator of rheumatoid arthritis (RA) activity in the body, but it may be useful in indicating how much fluid inflammation there is in a specific joint. Researchers measured the amount of MMP-1 in joint fluid and blood samples from 41 patients with RA and found that MMP-1 levels did not reflect C reactive protein or MMP-1 levels in blood. MMP-1 levels in joint fluid did, however, correspond to the amount of joint fluid inflammation. Neither MMP-1 levels nor MMP-1 activity corresponded with levels of the tissue inhibitor of MMP. The release of MMPs into joint fluid causes cartilage to deteriorate, as happens in advanced RA.

Author: Sakurai, Minoru, Maeda, Shingo, Seki, Masayuki, Sawai, Takashi, Uzuki, Miwa, Takahashi, Yuichi, Omoto, Hiroshi
Publisher: British Medical Association
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 1995
Physiological aspects, Synovial fluid, Collagenases

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Circadian melatonin and cortisol levels in rheumatoid arthritis patients in winter time: a north and south Europe comparison

Article Abstract:

Circadian melatonin and cortisol levels in patients with rheumatoid arthritis during winter period in Estonia and Italy are compared.

Author: Cutolo, M., Maestroni, G.J.M., Otsa, K., Aakre, O., Villaggio, B., Capellino, S., Montagna, P., Fazzuoli, L., Veldi, T., Peets, T., Hertens, E., Sulli, A.
Publisher: British Medical Association
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 2005
Italy, Melatonin

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The development of the EULAR-OMERACT rheumatoid arthritis MRI reference image atlas

Article Abstract:

The details on magnetic resonance imaging results to examine rheumatoid arthritis are examined.

Author: Bird, P., Edmonds, J., Conaghan, P., Ejbjerg, B., McQueen, F., Lassere, M., Peterfy, C., Shnier, R., Connor, P.O., Haavardsholm, E., Emery, P., Genant, H., Ostergaard, M.
Publisher: British Medical Association
Publication Name: Annals of the Rheumatic Diseases
Subject: Health
ISSN: 0003-4967
Year: 2005
Australia, Usage, Magnetic resonance imaging

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Subjects list: Analysis, Diagnosis, Rheumatoid arthritis
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