Developmental outcome of preterm infants with transient neuromotor abnormalities

Article Abstract:

Transient neurologic abnormalities that occur among premature infants early in life do not appear to predict neurologic abnormalities or delays in cognitive development later in life. Of 112 premature infants, 84 demonstrated normal neuromotor development at both six months and 15 months. Twenty-eight had abnormal neuromotor development at six months but normal neuromotor development by 15 months and were classified as transiently abnormal. Infants classified as transiently abnormal at six months had significantly lower weight, height and head circumference at birth than the infants classified as normal. Although neurological abnormalities resolved by age 15 months among the transiently abnormal, infants in this group still had lower mental development scores than the normal infants through age two. However, by age four, there were no significant differences in cognitive development between the two groups.

Infants (Premature), Premature infants, Infant development, Cognition disorders, Cognitive disorders

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A controlled trial of dexamethasone in preterm infants at high risk for bronchopulmonary dysplasia

Article Abstract:

The study tested whether the use of dexamethasone, an anti-inflammatory steroid, would lower the disease rate in premature infants with bronchopulmonary dysplasia, a chronic infant lung diseaseresulting in abnormal lung development. One group of children was given dexamethasone for 42 days, another for 18 days and another received a solution of no pharmacological value. Infants who received dexamethasone for the full 42 days were weaned form artificial respiration and from supplemental oxygen much more quickly than the other two groups. Use of the steroid did not cause any noticeable complications.

Research, Causes of, Dexamethasone, Bronchopulmonary dysplasia

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Good news for gene therapy

Article Abstract:

A study reveals that the setback which was caused due to gene therapy, which involves infants born with X-linked severe combined immunodeficiency (SCID), can possibly reduce the likelihood that such an event will recur.

United States, Care and treatment, Analysis, Gene therapy, Severe combined immunodeficiency

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