Differential alterations in responsiveness in particulate and soluble guanylate cyclases in pregnant guinea pig myometrium

Article Abstract:

During pregnancy, soluble guanylate cyclase becomes less responsive to nitric oxide and particulate guanylate cyclase becomes more responsive to natriuretic peptides. Guanylate cyclase produces cyclic GMP, which increases during pregnancy but decreases a few days before labor. It may be involved in preventing uterine contractions during pregnancy.

Pregnancy, Cyclic guanylic acid, Cyclic guanosine monophosphate

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Myometrial thickness during human labor and immediately post partum

Article Abstract:

Research has ben conducted on asymmetric uterine growth during pregnancy caused by muscle cell hypertrophy. The authors report widespread thinning of the myometrium during active labor.

United States, Health aspects, Analysis, Growth, Hypertrophy, Childbirth, Delivery (Childbirth), Muscle cells, Obstetrics, Company growth, Uterus, Pregnant, Pregnant uterus

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The presence and function of phosphodiesterase type 5 in the rat myometrium

Article Abstract:

Cyclic nucleotide phosphodiesterases (PDEs) are a diverse enzyme group with multiple regulatory properties and wide tissue distribution. The type 5 isoform is the target of specific antagonists and the hypothesis that PDE-5 is present in rat myometrium and modulates myometrial activity is tested.

Phosphodiesterases

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