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Melanoma

Article Abstract:

The Clarke model of the progression of melanoma emphasizes the stepwise transformation of melanocytes to melanoma, depicting the proliferation of melanocytes in the process of forming nevi and the subsequent development of cisplatin, hyperplasia, invasion, and metastasis. A discussion on connections between molecular pathways and risk factors for melanoma is presented, together with the different steps of neoplastic transformation, and the patterns of molecular changes in melanoma.

Author: Miller, Arlo J., Mihm, Martin C., Jr.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2006
Analysis, Risk factors, Melanoma, Hyperplasia, Disease/Disorder overview

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Withdrawal of long-term cabergoline therapy for tumoral and nontumoral hyperprolactinemia

Article Abstract:

Patients with a pituitary gland tumor called a prolactinoma can stop taking the drug cabergoline provided they have normal blood levels of prolactin and no evidence of a tumor. This was the conclusion of a study of 200 patients. However, these patients should have regular checkups to detect any recurrence of the tumor once the drug is discontinued.

Author: Colao, Annamaria, Di Sarno, Antonella, Cappabianca, Paolo, Di Somma, Carolina, Pivonello, Rosario, Lombardi, Gaetano
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
Drug therapy, Prolactinoma

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