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Tolerability and safety of HIV protease inhibitors in adults

Article Abstract:

Protease Inhibitors (PI)-based antiretroviral therapy (ART) has dramatically improved the prognosis for HIV-infected patients. PIs remain a critical component of successful ART. The two recently approved PIs demonstrate improved subjective and metabolic tolerability profiles, which should lead to increased choice of PI-based as a component of antiretroviral treatment.

Author: Kumar, Princy, Sax, Paul E.
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2004
Science & research, Research, Protease inhibitors

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Cost-effectiveness of enfuvirtide in treatment-experienced patients with advanced HIV disease

Article Abstract:

The potential long-term clinical impact and cost-effective of enfuvirtide (ENF) in HIV patients is determined. The results revealed that in highly treatment-experienced patient, ENF plus an optimized background regimen (OBR) provides substantial gains in quality-adjusted life expectancy compared with an OBR alone.

Author: Weinstein, Milton C., Hong Zhang, Freedberg, Kenneth A., Losina, Elena, Kimmel, April D., Goldie, Sue J., Paltiel, A. David, Sax, Paul E., Walensky, Rochelle P., Muccio, Tammy M.
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2005
United States, HIV infection, Drug therapy, HIV infections, Dosage and administration

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Subjects list: Care and treatment, HIV patients, Antiviral agents, Antiretroviral agents
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