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Do worldwide outbreaks mean tuberculosis again becomes 'captain of all these men of death'?

Article Abstract:

The incidence of drug-resistant tuberculosis is higher in patients who are infected with the human immunodeficiency virus (HIV). Before 1984, 10% of tuberculosis bacteria taken from patients were drug-resistant, but the number increased to 52% after 1984. Individuals infected with HIV are more vulnerable to tuberculosis infection and are more likely to develop active tuberculosis than healthy individuals. Tests to detect tuberculosis infection are often unreliable in HIV-infected individuals. New York State public health officials are trying to identify individuals exposed to drug-resistant tuberculosis, and are screening prisoners for the disease. Treatment of tuberculosis patients is difficult because of poor patient compliance, and several anti-tuberculosis drugs are not available. The Centers for Disease Control wants pharmaceutical companies to develop more effective drugs. Public health experts are considering the use of a tuberculosis vaccine in high-risk individuals, and New York State may open a sanitarium for tuberculosis patients.

Author: Marwick, Charles
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1992
Drug therapy, Tuberculosis

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Animal Feed Antibiotic Use Raises Drug Resistance Fear

Article Abstract:

Scientists, physicians, and policymakers met at Georgetown University in Washington, DC, to discuss the human health implications of antibiotic use in feed animals. Antibiotics used to promote growth in cattle and other feed animals may encourage the development of drug-resistant organisms. The use of virginiamycin, a new antibiotic drug, has resulted in poultry that harbor bacteria resistant to Synercid, a new antibiotic intended to treat vancomycin-resistant enterococcal infections.

Author: Marwick, Charles
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1999
Health aspects, Statistical Data Included, Usage, Antibiotics, Antibiotics in animal nutrition, Animal nutrition, Veterinary antibiotics, Synercid (Medication)

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Protecting Subjects of Clinical Research

Article Abstract:

The National Bioethics Advisory Commission has recommended that the Office of Protection From Reseach Risks (OPRR) be moved to the Department of Health and Human Services and expanded. Research subjects in medical clinical trials only receive the protective oversight of OPRR if the study is federally funded. In order to improve the safety of human experimentation, the Commission recommends that all research, funded publicly or privately, should be overseen by OPRR.

Author: Marwick, Charles
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1999
Laws, regulations and rules, Services, Clinical trials, United States. National Institutes of Health, Human experimentation in medicine, Human medical experimentation

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Subjects list: Causes of, Drug resistance in microorganisms, Microbial drug resistance, United States
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