Effect of aspirin in pregnant women is dependent on increase in bleeding time

Article Abstract:

Pregnant women at risk of preeclampsia should be given enough aspirin to significantly increase their bleeding time. Preeclampsia is a complication of pregnancy characterized by hypertension and abnormal blood clotting. Consequently, pregnant women at risk for preeclampsia are often given aspirin, which inhibits blood clotting. Researchers analyzed aspirin use by 187 pregnant women at risk of preeclampsia. The treatment was most successful when begun early in pregnancy. Also, a dose that led to an increase in bleeding time equal to or greater than two minutes was most successful.

Care and treatment, Pregnant women

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Prevention of preeclampsia: a big disappointment

Article Abstract:

Researchers have had little success in identifying drugs or substances which might prevent preeclampsia in pregnancy. Preeclampsia is a complex disorder characterized by high blood pressure and excessive secretion of protein in the urine, and a major cause of illness and death in pregnant women and their fetuses. Aspirin, calcium, magnesium, zinc, fish oil, and antihypertensive drugs have proven of little or no benefit in preventing the condition.

United States, Antihypertensive drugs, Antihypertensive agents, Calcium, Calcium (Chemical element), Fish oils, Magnesium, Magnesium (Metal), Zinc compounds

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Preeclampsia prevention: lessons from the low-dose aspirin therapy trials

Article Abstract:

More research is needed to identify pregnant women who will benefit from taking aspirin to prevent pre-eclampsia. Pre-eclampsia is a serious complication of pregnancy. Nineteen clinical trials have shown that some women benefit from taking aspirin, but others do not.

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