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Effect of proton-pump inhibitor therapy on diagnostic testing for Helicobacter pylori

Article Abstract:

Physicians should wait at least two weeks after treatment with proton pump inhibitors ends before testing patients for Helicobacter pylori. Helicobacter pylori is a bacterium responsible for some gastrointestinal diseases and proton pump inhibitors are commonly used to eliminate the infection. However, when given alone, these drugs suppress the organism, which may lead to false-negative tests. In a study of 93 patients taking a proton pump inhibitor, 33% had a false-negative test while taking the drug. After the drug was stopped, 9% still had a false-negative test at three days, 3% had one at seven days, and none had one at 14 days.

Author: Laine, Loren, Estrada, Roque, Trujillo, Maria, Knigge, Kandice, Fennerty, M. Brian
Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 1998
Diagnosis, Antiulcer agents, Lansoprazole, Antiulcer drugs

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Helicobacter pylori infection and the risk for heart attacks in men

Article Abstract:

Exposure to Helicobacter pylori does not appear to increase a man's risk of having a heart attack, according to a study of 890 male doctors participating in the Physicians' Health Study. Researchers believe some bacteria might cause atherosclerosis by causing inflammation of the inside of blood vessels.

Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 2001
Risk factors, Heart attack, Helicobacter pylori

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Improvement of precancerous changes in the stomach after treatment of Helicobacter pylori infection

Article Abstract:

Treatment of Helicobacter pylori may reverse some precancerous changes in the stomach, according to a study of 163 patients. Helicobacter pylori is a bacterium that has been linked to stomach inflammation and ulcers.

Publisher: American College of Physicians
Publication Name: Annals of Internal Medicine
Subject: Health
ISSN: 0003-4819
Year: 2001
Care and treatment, Precancerous conditions

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Subjects list: Health aspects, Helicobacter infections
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