Effects of acadesine on myocardial infarction, stroke, and death following surgery: a meta-analysis of the 5 international randomized trials

Article Abstract:

Giving patients having coronary artery bypass graft (CABG) surgery acadesine before and during surgery appears to reduce the incidence of heart attack and heart attack death during or shortly after the operation. Researchers combined data from five studies totalling 4,043 CABG patients in which patients were randomly assigned to receive intravenous acadesine or a placebo. Acadesine reduced the incidence of heart attack during or shortly after surgery by one-quarter and cut the incidence of heart-attack related death in half. Thirteen percent of the placebo group died within the first four days versus 1.5% of the acadesine group.

Complications and side effects, Physiological aspects, Surgery, Heart attack, Stroke (Disease), Postoperative complications, Nucleosides, Purines

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Use of an automated, load-distributing band chest compression device for out-of-hospital cardiac arrest resuscitation

Article Abstract:

A study was conducted to compare resuscitation outcomes before and after an urban emergency medical services (EMS) system switched from manual cardiopulmonary resuscitation (CPR) to load-distributing band (LDB) CPR. It was found that compared with resuscitation using manual CPR, a resuscitation strategy using LDB-CPR on EMS ambulances leads to improved survival to hospital discharge in adults with out-of-hospital nontraumatic cardiac arrest.

Usage, Cardiovascular equipment, Cardiac resuscitation

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Place of death after stroke-United states, 1999-2002

Article Abstract:

Trends in the place of death among all stroke decedents, the proportion of stroke deaths occurring before emergency assistance arrives, and characteristics associated with place of death is summarized. Results reveal that early patient and bystander recognition of stroke symptoms and timely action in calling for emergency assistance might reduce the number of stroke deaths.

Statistics

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