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Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis

Article Abstract:

A randomized, double blind, and controlled study was conducted to confirm the observations of sustained clinical improvements by the use of rituximab for patients with rheumatoid arthritis. The results show that a single course of two infusions of rituximab can improve the disease symptoms.

Author: Emery, Paul, Shaw, Tim, Edwards, Jonathan C.W., Szczepanski, Leszek, Szechinski, Jacek, Filipowicz-Sosnowska, Anna, Close, David R., Stevens, Randall M.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
Rheumatoid arthritis, Rituximab

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CGRP-receptor antagonists - A fresh approach to migraine therapy?

Article Abstract:

Patients with migraine experience severe headache along with nausea, vomiting and sensitivity to light and sound. Studies reveal that calcitonin gene-related peptide d (CGRP)-receptor antagonist BIBN 4096 BS is an effective, well-tolerated treatment for migraine.

Author: Durham, Paul L.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
United Kingdom, HEALTH SERVICES, Ambulatory Health Care Services, Therapeutic Procedures, Therapeutics, Migraine

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Subjects list: Care and treatment, Research
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