Elevation of both maternal and fetal extracellular circulating deoxyribonucleic acid concentrations in the plasma of pregnant women with preeclampsia

Article Abstract:

Doctors have shown for the first time that pregnant women with preeclampsia not only have increased blood levels of fetal DNA but also increased amounts of DNA from the woman's own body. Preeclampsia is a serious complication of pregnancy.

DNA, Fetal blood

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Maternal and fetal inherited thrombophilias are not related to the development of severe preeclampsia

Article Abstract:

A predisposition toward increased blood clotting does not appear to increase a woman's risk of preeclampsia of the HELLP sydnrome, according to a study of 110 pregnant women with preeclampsia and 97 healthy pregnant women. Preeclampsia and the HELLP syndrome are serious complications of pregnancy that involve abnormal blood clotting, among other symptoms.

Health aspects, Risk factors, Blood clotting disorders, Blood coagulation disorders, HELLP syndrome

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Plasma and placental calcitonin gene-related peptide in pregnancies complicated by severe preeclampsia

Article Abstract:

A regulatory protein known as calcitonin gene-related peptide (CGRP) may not be involved in the development of preeclampsia. Preeclampsia is a serious complication of pregnancy involving high blood pressure and protein in the urine. Researchers compared the levels of CGRP in blood from mothers and fetuses and in placental tissue from preeclamptic pregnancies to those from normal pregnancies and to blood from women who were not pregnant. CGRP levels were similar among preeclamptic, normal pregnant, and nonpregnant women. CGRP levels in fetuses and in placental tissues were similar in preeclamptic and normal pregnancies. These findings differ from those from previous studies suggesting that CGRP levels are low in preeclamptic pregnancies.

Measurement, Pregnancy proteins

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