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Familial aggregation of Parkinson's disease in Iceland

Article Abstract:

Parkinson's disease may have a genetic component, according to a study of 772 patients with Parkinson's disease in Iceland. According to the deCODE genetics, Inc. database of 610,920 Icelanders, those who were siblings of Parkinson's disease had 7 times the risk of Parkinson's disease, those who were offspring had 3 times the risk, and those who were nieces and nephews had 3 times the risk.

Author: Stefansson, Kari, Sveinbjornsdottir, Sigurlaug, Hicks, Andrew A., Jonsson, Thorlakur, Petursson, Hjorvar, Guemundsson, Gretar, Frigge, Michael L., Kong, Augustine, Gulcher, Jeffrey R.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
Research, Parkinson's disease, Parkinson disease, Familial diseases, deCODE genetics Inc., DCGS

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Familial risk of lung carcinoma in the Icelandic population

Article Abstract:

Study was conducted to investigate the contribution of genetic factors to the risk of developing lung carcinoma in the Icelandic population. Tobacco smoke plays a dominant role in the pathogenesis of this disease, even among those individuals who are genetically predisposed to lung carcinoma underscoring the importance of genetic predisposition in the development of lung carcinoma.

Author: Stefansson, Kari, Gulcher, Jeffrey R., Gudnason, Vilmundur, Jonsson, Steinn, Amundadottir, Laufey T., Thorsteinsdottir, Unnur, Kong, Augustine, Kong, Gudbjartsson, Daniel F., Kristjansson, Kristleifur, Jonsson, Hjortur H., Arnason; Sigurdur, Isaksson, Hlegi J., Hallgrimsson, Jonas
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2004
Smoking, Lung cancer

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A genetic risk factor for periodic limb movements in sleep

Article Abstract:

The possibility that periodic limb movement and restless leg syndrome during sleep may be related to inherited genes is presented.

Author: Stefansson, Kari, Kong, Augustine, Gulcher, Jeffrey R., Thorsteinsdottir, Unnur, Kristjansson, Kristleifur, Gudbjartsson, Daniel, Hardarson, Gudmundur A., Stefansson, Hreinn, Palsson, Stefan, Sigmundsson, Thordur, Pertursson, Hjorvar, Ingason, Andres, Thorgeirsson, Thorgeir E., Rye, David B., Hicks, Andrew, Sigurdsson, Albert P., Beck, Joseph M., Rosen, Ami, Waddy, Salina, Trotti, Lynn M., Eiriksdottir, Ingibjorg, Soebech, Emilia, Bliwise, Donald, Iranzo, Alex, Gudmundsson, Larus J., Thambisetty, Madhav
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
Restless legs syndrome

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Subjects list: Genetic aspects, Iceland, Risk factors
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