Overexpression of the alpha(1B)-adrenergic receptor causes apoptotic neurodegeneration: multiple system atrophy

Article Abstract:

Research is presented on the role of alpha(1B)-adrenergic receptors within the central nervous system, particularly in diseases such as Shy-Drager syndrome which involve multiple system atrophy. Findings suggest that alpha(1B)-adrenergic receptor signaling directly participates in the pathology; implications are discussed.

Statistical Data Included, Physiological aspects, Cell death, Nervous system, Epinephrine, Nerve degeneration, Adrenergic receptors

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Neutralizing antibodies take a swipe at HIV in vivo

Article Abstract:

Neutralizing antibodies provide a defense against many pathogens and are highly important for HIV-1 vaccines. These antibodies and the conserved epitopes are of considerable interest for passive immunotherapy and for new vaccine immunogens, which aim to elicit an effective neutralizing antibody response.

Care and treatment, Usage, HIV infection, HIV infections, AIDS vaccines, Viral antibodies, Antibodies

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