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Functional analysis of naturally occurring mutations in the open reading frame of CCR5 in HIV-infected Chinese patients and healthy controls

Article Abstract:

Polymorphism of the HIV coreceptor CC chemokine receptor (CCR) 5 in 1099 Chinese adults residing in Hong Kong, including 785 HIV-negative healthy donors and 314 HIV-positive patients are studied. It is concluded that the CCR5 mutation in not uncommon in Chinese populations, although the frequency was low in cohort of HIV patients and healthy individuals.

Author: Xiu-Ying Zhao, Ka-Hing Wong, Kenny C.W. Chan, Fai Ng., Chris C.S. Chan, Dan Han, Wing-Cheong Yam, Kwok-Yung Yuen, Mun-Hon Ng, Bo-Jian Zheng
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2005
Hong Kong

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Fat distribution in HIV-infected women in the United States: DEXA substudy in the women's interagency HIV study

Article Abstract:

A study is done on the Women's Interagency HIV Study to examine fat distribution in a well-characterized cohort of HIV-positive and HIV-negative women in the United States. The results showed that most of the both HIV-positive and HIV-negative women were overweight.

Author: Mulligan, Kathleen, Anastos, Kathryn, Hessol, Nancy A., Freeman, Ruth, Justman, Jessica, Wichienkuer, Paula, Robinson, Esther
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2005
United States, Women, Risk factors, Obesity, Women's health

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Biochemical and HIV-1 coreceptor properties of K26R, a new CCR5 variant in China's Sichuan population

Article Abstract:

Five chemokine receptor (CCR5) coding region variants are identified in a Chinese population. A study of the K26R chemokine receptor activity and HIV coreceptor properties compared with wild type CCR5 and G106R is also presented.

Author: Tran, Ton, Hui Xing, Ma, Liying, Theodorou, Oiannis, Dudoit, Yasmine, Shao, Yiming, Capoulade-Metay, Corinne, Debre, Patrice, Bismuth, Geroges, Jiaping Chen, Pancino, Gianfranco
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2005
China

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Subjects list: Health aspects, Care and treatment, Research, Diagnosis, HIV infection, HIV infections, Chinese, Chinese (Asian people), Chemokine receptors
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