Gastroesophageal reflux induced by exercise in healthy volunteers

Article Abstract:

Healthy volunteers were asked to perform various exercises before and after meals to study the effects of different types of physical activity on gastroesophageal reflux, which is the backward flow of contents of the stomach back into the esophagus. Gastroesophageal reflux typically causes heartburn, stomach upset or chest pain. Exercises included two types of aerobic exercises: running, which causes a high degree of body agitation; and stationary bicycling, which causes little agitation to the body. In addition, nonaerobic sports were measured by studying the effect of different types of weight lifting on gastroesophageal reflux. Vigorous exercise, such as running, caused reflux, even in normal subjects. Aerobic exercises with less bodily agitation, for example stationary bicycling, produced less reflux. The weight routine caused gastroesophageal reflux in some people. Exercise after meals produced more cases of reflux than exercise before meals, but the pattern of reflux was similar in both cases.

Exercise, Exercise physiology

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Gastroesophageal reflux in runners

Article Abstract:

Although running on a regular schedule improves fitness, many runners experience heartburn, a feeling of stomach fullness, regurgitation, and frequent belching. One study showed that vigorous exercise, such as running, could cause gastroesophageal reflux, the backflow of stomach contents into the esophagus, in healthy persons. The potential of distance running to cause reflux was assessed in 14 healthy subjects. The ability of the anti-ulcer drug ranitidine to decrease the exposure of the esophagus to stomach acid as a result of reflux was also evaluated. The results reveal that gastroesophageal reflux occurred more frequently during running than during rest periods. Episodes of gastroesophageal reflux were associated with belching. Ranitidine, given by mouth one hour before running, decreased exposure of the esophagus to acid during running. (Consumer Summary produced by Reliance Medical Information, Inc.)

Health aspects, Prevention, Running, Ranitidine

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The contribution of gastroesophageal reflux to chest pain in patients with coronary artery disease

Article Abstract:

Gastroesophageal reflux may contribute to the cause of chest pain in patients with coronary artery disease. Gastroesophageal reflux is a disorder characterized by backflow of the acidic contents of the stomach into the esophagus. Among 34 patients with coronary artery disease who were experiencing chest pain despite treatment for their illness, 30 patients (88%) experienced chest pain while being monitored for esophageal reflux. Of the 164 episodes of chest pain experienced by these patients, 38 (23%) were caused by acid reflux, six (4%) were caused by reduced blood flow to the heart and 120 (73%) had no diagnosable cause. Twenty patients who experienced chest pain associated with acid reflux underwent treatment for gastroesophageal reflux. Thirteen of these patients improved or no longer experienced any episodes of chest pain.

Complications and side effects, Coronary heart disease, Chest pain

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