HIV Prevalence, Risk, and Partner Serodiscordance Among Pregnant Women in Bangkok

Article Abstract:

Sex appears to be a common risk factor for HIV infection among pregnant women in Thailand. Researchers studied 342 HIV-positive pregnant women and 344 HIV-negative pregnant women at a hospital prenatal clinic. HIV infection was associated with more than one lifetime sexual partner, a history of sexually transmitted disease, and a partner who engages in high-risk behavior. Twenty-six percent of partners of HIV-infected women were also infected. Sex with their current sex partner, generally the husband or live-in partner, was the only risk factor for 52% of HIV-positive women.

Health aspects, Women, Risk factors, Thailand, HIV infection in women

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Safety and efficacy of lamivudine-zidovudine combination therapy in zidovudine-experienced patients: a randomized controlled comparison with zidovudine monotherapy

Article Abstract:

Lamivudine in combination with zidovudine appears to be more effective in HIV infection than zidovudine alone. A total of 223 HIV-infected patients were randomly allocated to take 200 milligrams (mg) of zidovudine 3 times a day, zidovudine plus 150 mg of lamivudine twice a day or zidovudine plus 300 mg of lamivudine twice a day. The combination of lamivudine at either dose with zidovudine was more effective in raising CD cell counts and lowering blood levels of the virus. This was also true in those patients who switched from zidovudine alone to zidovudine/lamivudine.

HIV infection, Antiviral agents

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Combination Prophylaxis for Prevention of Maternal-Infant HIV Transmission: Beyond 076

Article Abstract:

The AIDS drug combination zidovudine-lamivudine can substantially reduce an HIV-infected pregnant woman's risk of transmitting the virus to her baby. Unfortunately, the treatment can adversely affect the baby and the virus can become resistant if the treatment lasts longer than one month.

Editorial, Lamivudine

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