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Specific amplification of parasite sequences reflects presence of viable organisms

Article Abstract:

Results of a study conducted by researchers William Jarra and Georges Snounou revealed live parasites in rodent malaria infections. They utilized polymerase chain reaction (PCR) assays to identify the parasites and determine the species. They also integrated a nested reaction to enhance the sensitivity of a described PCR detection assay. The amplification of parasite sequences enabled them to determine the presence of damaged or killed parasites.

Author: Clark, Cathy
Publisher: NewsRX
Publication Name: World Disease Weekly Plus
Subject: Health
ISSN:
Year: 1998
Research, Usage, Mice, Mice (Rodents), Polymerase chain reaction, Malaria, Jarra, William, Snounou, Georges

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Dried blood spot technology helps identify iron deficiency

Article Abstract:

Results of a review of studies conducted between 1960 and 1983 pegged the global prevalence of anemia at 30%. Findings also indicated that determining iron-deficiency anemia could be correlated with measuring serum ferritin and transferrin receptor in dried blood spots. Moreover, results showed that ferritin concentration in dried blood samples is threefold higher than serum assays because of is release from hemolyzed erythrocytes.

Author: Clark, Cathy
Publisher: NewsRX
Publication Name: World Disease Weekly Plus
Subject: Health
ISSN:
Year: 1998
Diagnosis, Measurement, Transferrin, Ferritin, Iron deficiency anemia

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