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Long-term complications of diabetes mellitus

Article Abstract:

A variety of long-term complications can develop in patients with diabetes mellitus. Diabetes mellitus is a disease that is characterized by abnormalities in glucose metabolism. Retinopathy is inflammation of the retina or degenerative, noninflammatory conditions of the retina. This type of complication occurs in most diabetes patients regardless of the form of the disease. Nephropathy, or kidney disease, occurs in 35% to 45% of diabetes patients. This complication is a more frequent cause of death than any other long-term complication of diabetes. Diabetic neuropathies are a group of disorders that affect the peripheral nervous system. The risk of developing a diabetic neuropathy usually increases with duration of the disease. Diabetes patients also have an increased risk of developing cardiovascular disease. Women with diabetes have the same risk of developing coronary artery disease as men with diabetes.

Author: Nathan, David M.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1993
Cardiovascular diseases, Causes of, Complications and side effects, Development and progression, Diabetic retinopathy, Diabetic nephropathies, Diabetic neuropathies, Diabetic angiopathies

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Finding new treatments for diabetes - How many, how fast ... how good?

Article Abstract:

The worldwide increase in the incidence of type 2 diabetes mellitus has necessitated development of effective medications for the management of the epidemic. Nine classes and more than 30 medications for the treatment of type 2 diabetes are available, but most of them are inadequately effective. Hence, it is advisable to ensure cost-effective use of clinically established medications instead of approving a new medication that has received limited testing.

Author: Nathan, David M.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
Drug therapy, Disease/Disorder overview

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Subjects list: Diabetes, Diabetes mellitus
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