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Hormone Replacement Therapy and High S Phase in Breast Cancer

Article Abstract:

Hormone therapy appears to stimulate the growth of certain types of breast cancer cells. Researchers analyzed certain characteristics of tissue samples from 331 postmenopausal women with breast cancer. Approximately half the women had used or were currently using hormone replacement therapy. Women who used hormone therapy were more likely to have cancer cells in the S phase, which is a sign of cell proliferation. However, this was only seen in women whose tumors had estrogen receptors.

Author: Oleske, Denise M., Cobleigh, Melody A., Norlock, Frances F., Starr, Alexander
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1999
Physiological aspects, Breast cancer, Cell proliferation

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Hepatitis C virus infections from a contaminated radiopharmaceutical used in myocardial perfusion studies

Article Abstract:

An outbreak of hepatitis C virus (HCV) infection among patients who had myocardial perfusion and received an infected radiopharmaceutical prepared at a pharmacy was investigated. Sixteen persons acquired HCV infection from the blood-contaminated radiopharmaceutical and it is suggested that nuclear pharmacies that handle biological products should follow appropriate aseptic technique to prevent contamination of sterile radiopharmaceuticals.

Author: Myers, Robert A., Roche, Jeffrey C., Fiore, Anthony E., Patel, Priti R., Larson, A. Kirsten, Castel, Amanda D., Ganova-Raeva, Lilia M., Roup, Brenda J., Farrell, Katherine P., Edwards, Leslie, Nainan, Omana, Blythe, David, Krick, John P.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
Radiopharmaceuticals, HIV infection, Drug therapy, HIV infections, Heart attack, Contamination, Cardiac patients

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A 60-year-old woman trying to discontinue hormone replacement therapy, 2 years later

Article Abstract:

The case of a 60-year-old woman with a family history of breast cancer and a personal history of surgical menopause at age 40 is discussed who had experienced severe hot flashes while trying to discontinue hormone therapy. It is noted that estrogen remains the most effective therapy for relief of vasomotor symptoms of menopause.

Author: Reynolds, Eileen E.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
Estrogen & Progestogen Preps, Women, Women's health, Menopause, Hormone replacement therapy

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Subjects list: Health aspects, Causes of, Hormone therapy, Estrogen, Estrogens, United States
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