How did the authors synthesize the data and make their conclusions?

Article Abstract:

Medical literature reviews combine data from a number of research studies to produce more definitive conclusions. Researchers select from the available research, concentrating on well-conducted experiments on similar topics. In order to accurately combine data from diverse clinical trials, reviewers make sure that patient selection criteria were similar, treatments and interventions were comparable, and that published data represents the totality of available research. Combined data are then synthesized to produce conclusions based on a larger patient population.

Analysis, Medical literature

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How did the authors find the studies and assess their quality?

Article Abstract:

Guidelines are given to help physicians interpret systematic reviews. These reviews usually evaluate the scientific literature on a particular topic and they usually focus on controlled clinical trials. However, it may be difficult to find all the clinical trials published on a certain topic. The authors of the review should specify the search technique they used and which sources they searched. They should also tell readers what criteria they used to evaluate the clinical trials, since many studies may be flawed in some way.

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Getting started

Article Abstract:

Systematic reviews of randomized controlled trials can enable physicians to keep up with some of the vast amounts of medical literature being produced. A systematic review can resolve differences between studies, point to new directions for research and identify therapies as either harmful or beneficial long before other studies can. If the review is focused on a clinical issue, and uses appropriate criteria for inclusion of articles, then it becomes easier to determine if any important data was missed.

Evaluation

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