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Hypertonic saline-dextran solutions for the prehospital management of traumatic hypotension

Article Abstract:

The effectiveness of giving accident victims a solution for pre-hospital treatment of life-threatening low blood pressure due to penetrating injuries was tested. The solution contained a higher salt concentration than the fluid that fills body cells (hypertonic) as well as dextran, a sugar. Forty-eight patients with penetrating injuries and a systolic (during contraction of the heart) blood pressure below 90 millimeters of mercury were given the hypertonic solution or a crystalloid plasmylate solution (a synthetic form of plasma, the clear fluid component of blood). There were no complications associated with administration of the hypertonic fluid, and execution of the procedure by paramedics was both safe and uniformly successful. The potential impact of this solution on emergency medical care and the favorable results of this study justify a larger evaluation of the effectiveness of this hypertonic solution in pre-hospital settings.

Author: Maningas, P.A., Mattox, K.L., Pepe, P.E., Jones, R.L., Feliciano, D.V., Burch, J.M.
Publisher: Elsevier B.V.
Publication Name: American Journal of Surgery
Subject: Health
ISSN: 0002-9610
Year: 1989
Health aspects, Glucose, Dextrose

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A new ACE inhibitor and two new angiotensin receptor blockers for hypertension

Article Abstract:

Three new drugs are available for treating hypertension: perindopril, telmisartan, and eprosartan. Perindopril, sold under the trade name Aceon, is an ACE inhibitor. ACE inhibitors block a specific enzyme that forms angiotensin II. However, other enzymes can also create angiotensin II. Consequently, angiotensin receptor blockers were created. These drugs block the binding of angiotensin II to its receptor. Telmisartan and eprosartan belong in this category of drugs. They are sold under the trade names Micardis and Teveten, respectively.

Publisher: Medical Letter, Inc.
Publication Name: Medical Letter on Drugs and Therapeutics
Subject: Health
ISSN: 0025-732X
Year: 1999
Evaluation, Product/Service Evaluation, Micardis (Medication), Teveten (Medication), Aceon (Medication)

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Witnessed arrest, but not delayed bystander cardiopulmonary resuscitation improves prehospital cardiac arrest survival

Article Abstract:

A study is conducted on the effect of witnessing a cardiac arrest on 874 patients at emergency medical service area by instituting a bystander CPR (ByCPR) and early administration of sodium bicarbonate monitoring survival parameters. Results showed overall survival rate was more when witnessed but not necessarily when ByCPR was performed by layman.

Author: Vukmir, R.B.
Publisher: British Medical Association
Publication Name: Emergency Medicine Journal
Subject: Health
ISSN: 1472-0205
Year: 2004
Science & research, Research, Emergency medical services, Cardiac arrest

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Subjects list: Hypertension, Drug therapy
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