Improved outcome of cytomegalovirus retinitis in AIDS patients after introduction of protease inhibitors

Article Abstract:

Protease inhibitors may slow the progression of cytomegalovirus (CMV) retinal infections in AIDS patients. Researchers analyzed the rate of progression of CMV retinal infections in 17 AIDS patients who were taking protease inhibitors for HIV infection and ganciclovir or foscarnet for CMV retinal infection. These patients had fewer CMV relapses compared to patients who didn't take protease inhibitors. Their survival rate at 17 months was 94%, which is an 89% increase compared to the survival rates of patients with CMV retinal infection before the use of protease inhibitors.

Development and progression, Cytomegalovirus infections, Retinal diseases

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Protease inhibitor use among a community sample of people with HIV disease

Article Abstract:

Many low-income and poorly educated HIV patients are not using protease inhibitors. Protease inhibitors in combination with traditional AIDS drugs can dramatically lower viral levels until they are undetectable. A survey of 1,034 HIV patients found that 66% were taking protease inhibitors and half were very knowledgable about the drugs. However, members of minority groups with low incomes and little education were less likely to use protease inhibitors.

Social status

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Disease-related factors associated with health-related quality of life in people with nonadvanced HIV disease assessed using an Italian version of the MOS-HIV Health Survey

Article Abstract:

A group of Italian researchers has confirmed the usefulness of the MOS-HIV Health Survey in the Italian language. This measures the impact of HIV infection during the early stages of the disease. It showed that the symptoms of early HIV infection have a significant impact on health.

Measurement, Quality of life

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