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Long-term survival and late deaths after allogeneic bone marrow transplantation

Article Abstract:

Bone marrow transplantation can effectively cure some types of leukemia and aplastic anemia, but transplant patients have a higher long-term mortality rate than the general population. Researchers compared 6,691 transplant recipients and a similar group of healthy people. Patients who were free of their disease two years after transplantation had an 89% chance of surviving five additional years, indicating that their diseases were probably cured by the procedure. Over many years, though, transplant patients had a higher risk of death, most commonly from cancer recurrence or graft-versus-host disease, than those in the general population.

Author: Klein, John P., Socie, Gerard, Wingard, John R., Weisdorf, Daniel, Kolb, Hans-Jochem, Passweg, Jakob R., Schouten, Harry C., Cahn, Jean-Yves, Rowlings, Philip A., Stone, Judith Veum, Henslee-Downey, P. Jean, Bredeson, Christopher
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1999
France, Patient outcomes, Mortality, Prognosis, Organ transplant recipients, Bone marrow, Bone marrow transplantation, Leukemia, Aplastic anemia

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Fluconazole prophylaxis against fungal colonization and infectdion in preterm infants

Article Abstract:

Giving premature babies the antifungal drug fluconazole appears to be effective in preventing serious fungal infection, according to a study of 100 premature babies. Premature babies are susceptible to infection by a fungus called Candida, which increases their risk of death.

Author: Kaufman, David, Boyle, Robert, Hazen, Kevin C., Patrie, James T., Robinson, Melinda, Donowitz, Leigh Goodman
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2001
Care and treatment, Evaluation, Prevention, Infants (Premature), Premature infants, Candidiasis, Fluconazole

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