Inhibitory effect of erythropoietin on contractility of human chorionic plate vessels

Article Abstract:

Inhibitory effect of erythropoietin on contractility of human chorionic plate vessels is described. It is detected that exposure to elevated levels of erythropoietin has an inhibitory effect on contractile responses in human placental chorionic plate arteries and this can improve fetoplacental perfusion in hypoxic fetuses with elevated erythrepoietin production.

United States, Health aspects, Placenta, Erythropoietin, Labour (Obstetrics)

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In vitro modulation of the expression of 15-hydroxy-prostaglandin dehydrogenase by trophoblast differentiation

Article Abstract:

Levels of the enzyme 15-hydroxy-prostaglandin dehydrogenase are higher in placental tissue called trophoblast when it is differentiating. This enzyme is involved in the metabolism of prostaglandins. Trophoblast differentiation is important for the proper functioning of the placenta.

Cell differentiation, Trophoblast, Trophoblasts

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Activity and expression of 15-hydroxyprostaglandin dehydrogenase in cultured chorionic trophoblast and villous trophoblast cells in chorionic explants at term with and without spontaneous labor

Article Abstract:

The metabolism of prostaglandins in the chorion decreases significantly during labor. This allows the prostaglandins to reach uterine tissue, where they stimulate the uterus to contract. The chorion is one of the fetal membranes.

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