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Intravenous morphine and topical tetracaine for treatment of pain in preterm neonates undergoing central line placement

Article Abstract:

The effectiveness and safety of topical tetracaine, intravenous morphine, or tetracaine plus morphine for alleviating pain in ventilated neonates during central line placement is determined. In this study of ventilated neonates undergoing central line placement, morphine and tetracaine plus morphine provided superior analgesia to tetracaine, however, morphine caused respiratory depression and tetracaine caused erythema.

Author: Lee, Charlene, Taddio, Anna, Yip, Amelia, Parvez, Boriana, McNamara, Patrick J., Shah, Vibhuti
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
Health aspects, Pain, Pain management, Dosage and administration, Tetracaine

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Routine morphine infusion in preterm newborns who received ventilatory support: a randomized controlled trial

Article Abstract:

An intravenous infusion of morphine may not benefit newborn babies in the intensive care unit, according to a study of 150 babies. The babies who received morphine had a similar response on three different pain tests as those who did not receive morphine. Morphine also did not improve the babies' intellectual function after they were discharged from the ICU.

Author: Anand, K.J.S., Simons, Sinno H.P., Dijk, Monique van, Lingen, Richard A. van, Roofthooft, Daniella, Duivenvoorden, Jugo J., Jongeneel, Niesje, Bunkers, Carin, Smink, Enna, Anker, John N. van den, Tibboel, Dick
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2003
Care and treatment, Evaluation

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Patient-controlled transdermal fentanyl hydrochloride vs intravenous morphine pump for postoperative pain: a randomized controlled trial

Article Abstract:

The efficacy and safety of using fentanyl hydrochloride in comparison to a standard intravenous morphine patient-controlled pump is examined. The transdermal patient-controlled analgesia (PCA) delivery system is equivalent to a standard morphine intravenous (IV) patient-controlled analgesia (PCA) regimen in postoperative pain management.

Author: Viscusi, Eugene R., Reynolds, Lowell, Chung, Frances, Atkinson, Linda E., Khanna, Sarita
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2004
Management dynamics, Practice, Prognosis, Clinical trials, Comparative analysis, Fentanyl, Pain, Postoperative, Postoperative pain

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Subjects list: United States, Infants (Newborn), Newborn infants, Morphine
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