Laparoscopy versus laparotomy: an evaluation of adhesion formation after pelvic and paraaortic lymphadenectomy in a porcine model

Article Abstract:

A laparoscopic technique may reduce adhesion formation following paraaortic and pelvic lymph node removal. Lymph nodes are often surgically removed to test for metastasis in cancer patients. Researchers compared the minimally invasive procedure with open surgical laparotomy in 90 hogs. Surgically opening the abdomen and peritoneum produced adhesions three weeks after surgery in every hog, while laparotomy without entering the peritoneum only produced adhesions in 21% of hogs. Laparoscopic surgery which breached the peritoneum produced adhesions in 30% of hogs.

Surgery, Lymph nodes, Abdomen, Adhesions, Laparoscopy, Lymph node excision

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Correlation of cyclooxygenase-2 (COX-2) and aromatase expression in human endometrial cancer: Tissue microarray analysis

Article Abstract:

A study was conducted to compare the prevalence of cyclooxygenase-2 (COX-2), aromatase, and hormone receptor immunohistochemical expression to well defined clinical-pathologic prognostic factors in a large group of surgically staged endometrial cancer patients. COX-2 expression significantly correlated with aromatase expression, suggesting that intratumoral production of estrogen in endometrial cancer may be an important mechanism in tumorigenesis.

Science & research, Research, Usage, Diagnosis, Drug therapy, COX-2 inhibitors, Observations, Endometrial cancer, Diagnostic immunohistochemistry, Tissue microarrays

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Pre-emptive analgesia in gynecologic surgical procedures: preoperative wound infiltration with ropivacaine in patients who undergo laparotomy through a midline vertical incision

Article Abstract:

Injecting an anesthetic into the skin of a woman's abdomen before she has abdominal surgery does not appear to be beneficial, according to a study of 68 women. The anesthetic was injected at the place where the incision would be made. This injection did not seem to prevent postoperative pain because women who got the injection used as much patient-controlled morphine after the operation as women who did not receive the injection.

Evaluation, Preoperative care, Injections, Hypodermic, Subcutaneous injections, Pain, Postoperative, Postoperative pain

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