Blood simple prion diagnostics

Article Abstract:

Issues related to the need for improving diagnostic tests for prion infections, such as that which occurs in bovine spongiform encephalopathy, are examined, focusing on possibilities for using a test that identifies the gene EDRF as a diagnostic marker.

Diagnosis, Diseases, Bovine spongiform encephalopathy, Prions, Prions (Proteins)

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Complement facilitates early prion pathogenesis

Article Abstract:

Research presented concerns the infective ability of prion diseases such as Creutzfeldt-Jakob disease and scrapie, focusing on the relationship between the immune and nervous systems. This study examines the role of immunoglobulins in the pathogenesis of prion diseases.

Statistical Data Included, Development and progression, Immunoglobulins, Scrapie

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Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration

Article Abstract:

The repeated administration of cytidyl guanosyl oligodeoxynucleotide (CpG - ODN) results in the destruction of lymphoid follicle and reduction in the immune response. Daily injection of 60 micrometer CpG-ODN dramatically alters the morphology and functionality of mouse lymphoid organs.

Science & research, Immunosuppression, Oligodeoxynucleotides

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