Malathion for head lice
Article Abstract:
Malathion, a phosphate-containing organic compound widely used as an insecticide, was recently approved in the form of a lotion for the treatment of head lice. Because it is more rapidly broken down by humans than by insects, malathion is not toxic in humans. Studies have demonstrated that this agent is effective in killing both the lice and its eggs, and attaches to the sulfur groups on hair. Adverse effects of the malathion lotion include stinging, especially of eyes, the release of foul-smelling sulfur and hydrogen compounds, and the flammability of the alcohol in which the malathion is dissolved. The dosage and application of this agent are described. In the United States, lindane has been commonly used to treat head lice, but has caused seizures and death in children and infants when large amounts were used to treat scabies, a skin disease caused by a type of insect. Lindane also has toxic effects on the blood when it is used as an insecticide or for treating pets. Another agent, permethrin, is more effective and safer than lindane in treating lice. Malathion solution is a safe, effective treatment for head lice, although its foul odor and required 8 to 12 hour application may discourage its use. (Consumer Summary produced by Reliance Medical Information, Inc.)
Publication Name: Medical Letter on Drugs and Therapeutics
Subject: Health
ISSN: 0025-732X
Year: 1989
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Drugs for head lice
Article Abstract:
There is no hard evidence for head lice becoming resistant to drugs. Frequent treatment failures are particularly associated with the use of pyrethrins combined with piperonyl butoxide. If the recommended treatment of 1% permethrin fails, leaving 5% permethrin on the hair over night may be worth a try. As a last resort, a single dose of oral ivermectin repeated after ten days seems to be effective. Malathion has been removed from the market while lindane causes both toxicity and drug resistance. Failure to comb out the lice and eggs completely may contribute to the alleged treatment decline.
Publication Name: Medical Letter on Drugs and Therapeutics
Subject: Health
ISSN: 0025-732X
Year: 1997
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Malathion for treatment of head lice
Article Abstract:
The FDA has approved Ovide Lotion for the treatment of head lice. It contains malathion in an isopropyl alcohol base. When applied to infected skin, it kills both the adult lice and their eggs. This occurs within 5 to 10 minutes. It also binds to hair, which would prevent further infection. One treatment may be sufficient to eradicate head lice. It causes no side effects and can be used for lice that have become resistant to other treatments.
Publication Name: Medical Letter on Drugs and Therapeutics
Subject: Health
ISSN: 0025-732X
Year: 1999
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