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Management of chronic obstructive pulmonary disease

Article Abstract:

Proper treatment of patients with chronic obstructive pulmonary disease (COPD) may reduce progression of the disease significantly. COPD is a group of chronic respiratory diseases characterized by a cough, sputum production, shortness of breath and airflow limitation. Educating patients and their families about COPD is one of the most important factors for successful treatment of the disease. Patients should also work with their physician to establish a set of realistic treatment goals. One treatment goal is to improve airflow. Inhaled beta2-adrenoreceptor agonists are one important group of drugs used to improve airflow in COPD patients. Other treatment goals are to manage complications caused by COPD and to increase functional capability. Some patients with COPD may undergo lung transplantation. Single lung transplantation is usually recommended over double lung transplantation for most COPD patients.

Author: Ferguson, Gary T., Cherniack, Reuben M.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1993
Respiratory tract diseases

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Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease

Article Abstract:

A study tests the hypothesis that a combination of the long-acting [beta]-agonist salmeterol and the inhaled corticosteroid fluticasone propionate reduces mortality among patients with chronic obstructive pulmonary disease (COPD), as compared with usual care. Results show that the reduction in death from all causes among patients with COPD in the combination-therapy group does not reach the predetermined level of statistical significance, but significant benefits are noted in all other outcomes among the patients.

Author: Ferguson, Gary T., Calverley, Peter M.A., Anderson, Julie A., Celli, Bartolome, Jenkins, Christine, Jones, Paul W., Yates, Julie C., Vestbo, Jorgen
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
United States, Drug therapy, Salmeterol, Dosage and administration, Fluticasone

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Management of Chronic Odstructive Pulmonary Disease

Article Abstract:

Chronic Obstructive Pulmonary Disease is a syndrome of progressive airflow limitation caused by chronic inflammation of the airways and lung parenchyma. The major goals include smoking cessation, symptom relief, improvement in physiological function and limitation of complications.

Author: Cherniack, Reuben M., Sutherland, Rand E.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
Science & research, Research, Causes of, Lung diseases

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Subjects list: Care and treatment, Lung diseases, Obstructive, Chronic obstructive lung disease
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