Hyperinsulinemia, Hyperglycemia, and Impaired Hemostasis: The Framingham Offspring Study

Article Abstract:

Elevated blood levels of insulin appears to cause excessive blood clotting, which could explain why diabetics have an increased risk of heart disease. In a study of approximately 3,000 people in the Framingham Offspring Study, those with elevated insulin levels also had elevated blood levels of proteins involved in blood clotting and low levels of proteins that break up blood clots. This was true even in people with normal blood sugar metabolism.

Physiological aspects, Blood clotting disorders, Diabetes, Blood coagulation disorders, Diabetes mellitus

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Triggering myocardial infarction by sexual activity: low absolute risk and prevention by regular physical exercise

Article Abstract:

The risk of having a heart attack after sexual intercourse is very small and can be reduced by regular physical exercise. Researchers used data from the Myocardial Infarction Onset Study, which interviewed 1,774 patients within 30 days of their heart attack. A total of 1,633 provided information about sexual activity and of these, 858 had been sexually active before their heart attack. Twenty-seven people reported having sexual intercourse during the two hours before their heart attack. The risk of having a heart attack after sexual intercourse was approximately twice the risk of having a heart attack any other time, but only within the two-hour period immediately following sex. Sexual intercourse was estimated to have caused a heart attack in less than 1% of the patients. Those who never exercised had three times the risk compared to those who exercised regularly. Patients with a history of heart attack or angina had no higher risk than those without such a history.

Health aspects, Heart attack, Sexual intercourse

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Metabolic risk factors worsen continuously across the spectrum of nondiabetic glucose tolerance: the Framingham Offspring Study

Article Abstract:

There appears to be no threshold above which people with certain risk factors will develop type 2, or adult onset, diabetes. Researchers measured certain risk factors for diabetes among 2,583 adults participating in the Framingham Offspring Study. Risk factors included obesity, hypertension, high blood lipid levels and high blood insulin levels. Thirteen percent had abnormal glucose tolerance and 5% were diagnosed with diabetes. Most of the risk factors increased on a continuous gradient between those with normal glucose tolerance and those with diabetes.

Analysis, Type 2 diabetes, Risk factors (Health)

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